Broader and deeper
protein content for optimized
discovery potential

Accelerate your research in oncology, neurology,
cardiology, infectious disease, and more

Introducing the SomaScan® 11K Assay

The SomaScan Assay, the industry-leading multiplex proteomics platform, is now capable of 11,000 protein measurements, enabling unmatched biomarker discovery and drug target identification research. This means you can now access half the human proteome.

The broadest, deepest disease coverage is now available to you

The new 11,000-plex menu is the most powerful proteomics solution today. Covering half of the genetically encoded human proteome, researchers can now decipher human biology by casting the widest net possible.

We took a broad approach to selecting new protein targets, and have mapped the protein coverage in biological processes and various disease areas, shown at right.


Source: DisGeNET

11K graphic, representing 11,000 measurable human proteins using the SomaScan Assay

Three targets, final one with an arrow in it.

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Detect proteins across every major biological pathway

% Proteomic Coverage by Platform for Selected Pathways

Source: KEGG

Our precision is backed by orthogonal validation

From our original 1,300-plex menu to today, we have maintained consistent quality metrics for specificity, sensitivity, reproducibility, and more.

Our customers rely on consistent quality, so they know their data is always accurate and meaningful. To meet their needs, SomaLogic provides the largest number of protein measurements and the greatest number of orthogonally confirmed protein reagents in the proteomics industry.

Primary validation of all SOMAmer® Reagents includes:

  • Determination of equilibrium binding affinity dissociation constant
  • Pull down assay of cognate protein from buffer
  • Demonstration of buffer dose response in the SomaScan Assay
  • Estimation of endogenous cognate protein signals in plasma
  • Required for inclusion in the SomaScan Assay

Primary validation of all SOMAmer Reagents: 11,000 - ChartOver 6,000 SOMAmer Reagents have multiple forms of orthogonal validation

Approximately 3,000 SOMAmer Reagents have undergone three or more types of specificity testing

11K graphic, representing 11,000 measurable human proteins using the SomaScan Assay

Three targets, final one with an arrow in it.

More targets = More discoveries
Analyze half the proteome – and discover even more.

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Learn how the SomaScan® Assay works

The SomaScan Assay profiles thousands of different proteins from only 55 µL of plasma/serum.

 

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SomaLogic’s CLIA-certified,
CAP-accredited laboratory
(USA)

SomaScan
Assay Services
are available at

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SomaLogic
Authorized Sites
(Worldwide)

SomaScan 11K Assay Services are available at:

11K graphic, representing 11,000 measurable human proteins using the SomaScan Assay

Three targets, final one with an arrow in it.

See the largest coverage of the genetically encoded human proteome

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Additional resources