Publications
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Current Publications Count: 578
Large-scale integration of the plasma proteome with genetics and disease
Mapping the proteo-genomic convergence of human diseases
Evaluating microbiome-directed fibre snacks in gnotobiotic mice and humans
A Microbiota-Directed Food Intervention for Undernourished Children
Duodenal Microbiota in Stunted Undernourished Children with Enteropathy
Plasma protein patterns as comprehensive indicators of health
Effects of microbiota-directed foods in gnotobiotic animals and undernourished children
Undulating changes in human plasma proteome profiles across the lifespan
Co-regulatory networks of human serum proteins link genetics to disease
Genomic atlas of the human plasma proteome
Genetic architecture of the cardiovascular risk proteome
Using aptamer-based technology to probe the plasma proteome for cardiovascular disease prediction
Assessment of variability in the plasma 7k SomaScan proteomics assay
The severity and duration of Hypoglycemia affect platelet-derived protein responses in Caucasians
Human Plasma Proteome During Normal Pregnancy
Plasma proteome profiling identifies changes associated to AD but not to FTD
Testican-2 is Associated with Reduced Risk of Incident ESKD
Multiomics study of nonalcoholic fatty liver disease
Thirty novel sequence variants impacting human intracranial volume
The 2022 Report on the Human Proteome from the HUPO Human Proteome Project
Components of the Complement Cascade Differ in Polycystic Ovary Syndrome
ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19.”
Markers of endothelial glycocalyx dysfunction in Clarkson disease
Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer’s disease
Is an MRI-derived anatomical measure of dementia risk also a measure of brain aging?
Proteomic Analysis of Effects of Spironolactone in Heart Failure With Preserved Ejection Fraction
Circulating Proteins Influencing Psychiatric Disease: A Mendelian Randomization Study
The circulating proteomic signature of alcohol-associated liver disease
Circulating proteomic profiles associated with endometriosis in adolescents and young adults
The minimum aptamer publication standards (MAPS guidelines) for de novo aptamer selection
Proteomic Biomarkers of Kleine-Levin Syndrome
Genome-wide screening identifies DNA methylation sites that regulate the blood proteome
Prospects for the application of aptamer based assay platforms in pathogen detection
Specialized interferon action in COVID-19
Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus
loci associated with carpal tunnel syndrome
Effects of age, amyloid, sex, and APOE epsilon4 on the CSF proteome in normal cognition
Assay-related differences in SuPAR levels: implications for measurement and data interpretation
Whole-exome sequencing identifies rare genetic variants associated with human plasma metabolites
Clinical applications of plasma proteomics and peptidomics: Towards precision medicine
Validation of disease-specific biomarkers for the early detection of bronchopulmonary dysplasia
Genetic architecture of band neutrophil fraction in Iceland
CCL17 acts as a novel therapeutic target in pathological cardiac hypertrophy and heart failure
Translation of aptamers toward clinical diagnosis and commercialization
Diagnostic Accuracy of Blood-Based Biomarker Panels: A Systematic Review
Effects of ivacaftor on systemic inflammation and the plasma proteome in people with CF and G551D
Chemical modifications for a next generation of nucleic acid aptamers
Analytical Considerations of Large-Scale Aptamer-Based Datasets for Translational Applications
Severe Iatrogenic Hypoglycemia Modulates the Fibroblast Growth Factor Protein Response
Proteomics in thrombosis research
Harnessing Big Data to Advance Treatment and Understanding of Pulmonary Hypertension
The Proteomic Profile of Interstitial Lung Abnormalities
Differential Proteomics of Cardiovascular Risk and Coronary Artery Disease in Humans
Placental proteins with predicted roles in fetal development decrease in premature infants
Proteomics technologies for cancer liquid biopsies
Advances in proteomic profiling of pediatric kidney diseases
Proteomic Studies of Psoriasis
Proteins and pathways in atrial fibrillation and atrial cardiomyopathy underlying cryptogenic stroke
Protein prediction for trait mapping in diverse populations
Diabetes, GDF-15 and incident heart failure: the atherosclerosis risk in communities study
Using the Plasma Proteome for Risk Stratifying Patients with Pulmonary Arterial Hypertension
A genome-wide association study of serum proteins reveals shared loci with common diseases
Coding and regulatory variants are associated with serum protein levels and disease
Proteins in the pathway from high red blood cell width distribution to all-cause mortality
Aptamers: Potential Diagnostic and Therapeutic Agents for Blood Diseases
Recent Developments in Clinical Plasma Proteomics-Applied to Cardiovascular Research
Influenza A virus uses PSMA2 for downregulation of NRF2-mediated oxidative stress response
Acute serum protein and cytokine response of single dose of prednisone in adult volunteers
Comparison of Proteomic Expression Profiles after Radiation Exposure across Four Different Species
Aptamers from random sequence space: Accomplishments, gaps and future considerations
The Plasma Proteome Fingerprint Associated With Circulating Carotenoids And Retinol In Older Adults
Integrated trajectories of the maternal metabolome, proteome, and immunome predict labor onset
Plasma P-selectin is an early marker of thromboembolism in COVID-19
Exercise plasma boosts memory and dampens brain inflammation via clusterin
Cross-validation of SARS-CoV-2 responses in kidney organoids and clinical populations
Synergistic insights into human health from aptamer- and antibody-based proteomic profiling
Plasma Proteomics of Renal Function: A Trans-ethnic Meta-analysis and Mendelian Randomization Study
Proteomic Approaches to Defining Remission and the Risk of Relapse in Rheumatoid Arthritis
Proteomic analysis of serum in workers exposed to diesel engine exhaust
Hypoglycemia-induced changes in complement pathways in type 2 diabetes
Multi-omic analysis in injured humans: Patterns align with outcomes and treatment responses
Integrated Multi-Omics for Novel Aging Biomarkers and Antiaging Targets
Predicting the probability of death using proteomics.
identifies proteins and pathways associated with dementia risk.
Human plasma proteomic profiles indicative of cardiorespiratory fitness.
Advances and Utility of the Human Plasma Proteome
Towards Building a Quantitative Proteomics Toolbox in Precision Medicine: A Mini-Review
Vitamin D association with the renin angiotensin system in polycystic ovary syndrome
The proteomic signature of recombinant Growth Hormone in recreational athletes
Advances in Aptamer-Based Biomarker Discovery
Replication study of plasma proteins relating to Alzheimer’s pathology.
Platelet Protein-Related Abnormalities in Response to Acute Hypoglycemia in Type 2 Diabetes.
Broadly effective metabolic and immune recovery with C5 inhibition in CHAPLE disease.
Multi-omics highlights ABO plasma protein as a causal risk factor for COVID-19.
BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection.
Type 2 Diabetes Coagulopathy Proteins May Conflict With Biomarkers Reflective of COVID-19 Severity.
Circulating testican-2 is a podocyte-derived marker of kidney health
Using ‘big data’ to disentangle aging and COVID-19.
The COVIDome Explorer researcher portal.
Effect of longevity genetic variants on the molecular aging rate.
Novel Murine Biomarkers of Radiation Exposure Using An Aptamer-Based Proteomic Technology.
Plasma Proteomic Profile Predicts Survival in Heart Failure with Reduced Ejection Fraction.
Proteomic signatures of inflammatory skin diseases: a focus on atopic dermatitis.
Metabolic syndrome and the plasma proteome: from association to causation.
Identification of Plasma Proteome Signatures Associated With Surgery Using SOMAscan
Association of a Serum Protein Signature With Rheumatoid Arthritis Development
Genetics meets proteomics: perspectives for large population-based studies
Circulating markers of NADH-reductive stress correlate with mitochondrial disease severity
Revealing the role of the human blood plasma proteome in obesity using genetic drivers
Proteomics in aging research: A roadmap to clinical, translational research
Blood biomarker discovery for autism spectrum disorder: A proteomic analysis
Biomarker-focused multi-drug combination therapy and repurposing trial in mdx mice
A meta-analysis uncovers the first sequence variant conferring risk of Bell’s palsy
DNA Damage, n-3 Long-Chain PUFA Levels and Proteomic Profile in Brazilian Children and Adolescents.
Pediatric and adult dilated cardiomyopathy are distinguished by distinct biomarker profiles.
Smoking induces sex-specific changes in the small airway proteome.
Validation of Chemokine Biomarkers in Duchenne Muscular Dystrophy.
Evolving a RIG-I antagonist: a modified DNA aptamer mimics viral RNA.
Serum levels of ACE2 are higher in patients with obesity and diabetes.
Functional Network Profiles in ARSACS Disclosed by Aptamer-Based Proteomic Technology
Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques
Genetic architecture of host proteins involved in SARS-CoV-2 infection
A Plasma Proteomic Signature of Skeletal Muscle Mitochondrial Function
Coronary Artery Disease and Type 2 Diabetes: A Proteomic Study
Comparison of Proteomic Assessment Methods in Multiple Cohort Studies
Reduced Apolipoprotein M and Adverse Outcomes Across the Spectrum of Human Heart Failure
Highly multiplexed proteomic assessment of human bone marrow in acute myeloid leukemia
Plasma proteomic profile of frailty
Serum protein biomarkers for juvenile dermatomyositis: a pilot study
Proteomic biomarkers of sleep apnea
Proteomic Signatures of Heart Failure in Relation to Left Ventricular Ejection Fraction
Proteomic and Metabolomic Correlates of Healthy Dietary Patterns: The Framingham Heart Study
Plasma proteomic profile of age, health span, and all-cause mortality in older adults
ZIKV Infection Induces DNA Damage Response and Alters the Proteome of Gastrointestinal Cells
Plasma proteomic signature of the risk of developing mobility disability: A 9-year follow-up
Increased Levels of Coagulation Factor XI in Plasma Are Related to Alzheimer’s Disease Diagnosis
Mechanisms of Sodium-Glucose Cotransporter 2 Inhibition: Insights From Large-Scale Proteomics
Targeting myostatin/activin A protects against skeletal muscle and bone loss during spaceflight
Multimodal immune phenotyping of maternal peripheral blood in normal human pregnancy
Modified nucleotides may have enhanced early RNA catalysis.
The Evolution of the Cardiovascular Biomarker Study.
Integrative phenotyping of glycemic responders upon clinical weight loss using multi-omics.
Using the circulating proteome to assess type I interferon activity in systemic lupus erythematosus.
Placenta accreta spectrum: biomarker discovery using plasma proteomics.
A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma.
Intense light as anticoagulant therapy in humans.
Identification of a unique temporal signature in blood and BAL associated with IPF progression.
Modified aptamers as reagents to characterize recombinant human erythropoietin products.
Circulating Protein Signatures and Causal Candidates for Type 2 Diabetes.
Aptamers and Antisense Oligonucleotides for Diagnosis and Treatment of Hematological Diseases.
Proteomics for personalized cardiovascular risk assessment: in pursuit of the Holy Grail.
Increased mTOR activation in idiopathic multicentric Castleman disease.
The prediction of early preeclampsia: Results from a longitudinal proteomics study
High-Throughput Identification of the Plasma Proteomic Signature of Inflammatory Bowel Disease.
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
Predicting health and life span with the deep plasma proteome.
Balanced event prediction through sampled survival analysis.
Neutrophil activation in systemic capillary leak syndrome (Clarkson disease)
Plasma proteome in multiple sclerosis disease progression
Osteitis is associated with dysregulated pro-osteoblastic activity in patients with nasal polyps
Vero cell proteomic changes induced by Zika virus infection
Application of an Aptamer-Based Proteomics Assay (SOMAscan™) in Rat Cerebrospinal Fluid
Plasma FGF-19 Levels are Increased in Patients with Post-Bariatric Hypoglycemia
Application of Proteomics Profiling for Biomarker Discovery in Hypertrophic Cardiomyopathy
Cancer protein biomarker discovery based on nucleic acid aptamers
A framework for multi-omic prediction of treatment response to biologic therapy for psoriasis
Fatigue in Sjögren’s syndrome: a search for biomarkers and treatment targets
Disease-specific and glucocorticoid-responsive serum biomarkers for Duchenne Muscular Dystrophy
Pulmonary Aptamer Signatures in Children’s Interstitial and Diffuse Lung Diseases
Metabolic and proteomic signatures of hypoglycemia in type 2 diabetes
A serum protein signature of APOE genotypes in centenarians
Activin type II receptor signaling in cardiac aging and heart failure
Circulating Biomarkers of Testosterone’s Anabolic Effects on Fat-Free Mass
Proteomics profiling and risk of new-onset atrial fibrillation: Framingham Heart Study
Characterization of Glycolytic Enzymes and Pyruvate Kinase M2 in Type 1 and 2 Diabetic Nephropathy
Zika virus infection disrupts astrocytic proteins involved in synapse control and axon guidance
Fine-Mapping of the Human Blood Plasma N-Glycome onto Its Proteome
Targeting Unique Epitopes on Highly Similar Proteins GDF-11 and GDF-8 with Modified DNA Aptamers
Biomarker discovery in cardiac allograft vasculopathy using targeted aptamer proteomics
The nucleolus functions as a phase-separated protein quality control compartment
Plasma proteomics identifies a ‘chemokine storm’ in idiopathic multicentric Castleman disease
Tracking disease progression non-invasively in Duchenne and Becker muscular dystrophies
Serum proteomic assessment of the progression of fracture healing
The impact of the glomerular filtration rate on the human plasma proteome
Novel application of aptamer proteomic analysis in cystic fibrosis bronchoalveolar lavage fluid
Benefit of apabetalone on plasma proteins in renal disease
“Scanning” into the future: the promise of SOMAScan technology for kidney disease
Aptamer-based proteomics of serum and plasma in acquired aplastic anemia
Sperm cell purification from mock forensic swabs using SOMAmerTM affinity reagents
Sputum transcriptomics reveal up-regulation of IL-1 receptor family members in severe asthma
Plasma from some cancer patients inhibits adenoviral Ad5f35 vector transduction of dendritic cells
Stability and reproducibility of proteomic profiles measured with an aptamer-based platform
Increased levels of circulating MMP3 correlate with severe rejection in face transplantation
Mistimed food intake and sleep alters 24-hour time-of-day patterns of the human plasma proteome
Classification of prostate cancer using a protease activity nanosensor library
Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation
Identification of novel systemic sclerosis biomarkers employing aptamer proteomic analysis
Plasma proteomic signature of age in healthy humans
Application of large scale aptamer-based proteomic profiling to “planned” myocardial infarctions
Integrative omics: harnessing the proteome to maximize the potential of the genome
Harnessing the power of proteomics to assess drug safety and guide clinical trials
Probing the virtual proteome to identify novel disease biomarkers
Cerebrospinal fluid protein changes in preeclampsia
Early identification of bronchopulmonary dysplasia using novel biomarkers by proteomic screening
Serum biomarker for diagnostic evaluation of pulmonary arterial hypertension in systemic sclerosis
A proteomic signature that reflects pancreatic beta-cell function
Proteomics: Clinical and research applications in respiratory diseases.
A proteomic clock of human pregnancy.
Clinical validation of a protein biomarker panel for non-small cell lung cancer
Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission
Modified aptamers enable quantitative sub-10-nm cellular DNA-PAINT imaging
Improving probes for super-resolution
Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator
A proteome-derived longitudinal pharmacodynamic biomarker for diffuse systemic sclerosis skin
Sexual dimorphism, age, and fat mass are key phenotypic drivers of proteomic signatures
Trisomy 21 causes changes in the circulating proteome indicative of chronic autoinflammation
Assessment of variability in the SOMAscan assay
Divergent roles for clusterin in lung injury and repair
A pilot characterization of the human chronobiome
Pharmacokinetic properties of DNA aptamers with base modifications
Genome-wide quantitative trait loci mapping of the human cerebrospinal fluid proteome
Identification of unique proteomic signatures in allergic and non-allergic skin disease
An immune clock of human pregnancy
A degradation fragment of type X collagen is a real-time marker for bone growth velocity
Large-scale proteomics identifies MMP-7 as a sentinel of epithelial injury and of biliary atresia
Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells
Activation of inflammatory and pro-thrombotic pathways in acute stress cardiomyopathy
Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity
Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease
GDF15 is a heart-derived hormone that regulates body growth
The prediction of late-onset preeclampsia: Results from a longitudinal proteomics study
Diagnosis and prognosis-review of biomarkers for mesothelioma
Molecular-based diagnosis of multiple sclerosis and its progressive stage
Vitamin B12 deficiency and impaired expression of amnionless during aging
Connecting genetic risk to disease end points through the human blood plasma proteome
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms
Aptamer-based proteomic profiling for prognostication in pulmonary arterial hypertension
Multiomic disease signatures converge to cytotoxic CD8 T cells in primary Sjogren’s syndrome
Selection of DNA aptamers with two modified bases
Development of a protein biomarker panel to detect non-small-cell lung cancer in Korea
The relationship of circulating proteins in early pregnancy with preterm birth
Fit for the eye: aptamers in ocular disorders
readat: an R package for reading and working with SomaLogic ADAT files
Respiratory mucosal proteome quantification in human influenza infections
Six-SOMAmer index relating to immune, protease and angiogenic functions predicts progression in IPF
An evaluation of an aptamer for use as an affinity reagent with MS: PCSK9 as an example protein
Embracing proteins: structural themes in aptamer-protein complexes
Clinical utility of serum biomarkers in Duchenne muscular dystrophy.
SELEX: How it happened and where it will go
Increased cerebrospinal fluid fibrinogen in major depressive disorder
Large-scale serum protein biomarker discovery in Duchenne muscular dystrophy
Practical synthesis of cytidine-5-carboxamide-modified nucleotide reagents
Influence of 5-N-carboxamide modifications on the thermodynamic stability of oligonucleotides
Improved preparation of 2 M triethylammonium bicarbonate
Proteomic methods for biomarker discovery and validation. Are we there yet?
Circulating proteomic signatures of chronological age
A candidate plasma protein classifier to identify Alzheimer’s disease.
Aptamer-based proteomic signature of intensive phase treatment response in pulmonary tuberculosis
Crystal structure of interleukin-6 in complex with a modified nucleic acid ligand
DTC-and-me: patient, provider, proteins and regulators.
Beyond antibodies: new affinity reagents to unlock the proteome.
Genetic associations with micronutrient levels identified in immune and gastrointestinal networks
Validation of a blood protein signature for non-small cell lung cancer
Systematic selection of modified aptamer pairs for diagnostic sandwich assays
Alzheimer’s disease biomarker discovery using SOMAscan multiplexed protein technology
Detection of Clostridium difficile toxins A, B and binary toxin with slow off-rate modified aptamers
Elucidating novel serum biomarkers associated with pulmonary tuberculosis treatment
Interaction with both ZNRF3 and LGR4 is required for the signalling activity of R-spondin
Aptamers and the RNA world, past and present
Life’s simple measures: unlocking the proteome
Protein signature of lung cancer tissues
Age-dependent changes in the cerebrospinal fluid proteome by slow off-rate modified aptamer array
Rapid histochemistry using slow off-rate modified aptamers with anionic competition
Aptamer-based multiplexed proteomic technology for biomarker discovery
High-content affinity-based proteomics: unlocking protein biomarker discovery
Expanding the chemistry of DNA for in vitro selection
Proteomics and diagnostics: Let’s get specific, again
Interlocking structural motifs mediate molecular discrimination by a theophylline-binding RNA
Let’s get specific: the relationship between specificity and affinity
High-resolution molecular discrimination by RNA