More than the sum of its parts: How harmonized proteomic data reveals meaning across disparate clinical cohorts

Reveal what fragmented data is missing

Proteomics data generated across sites, time points, and workflows can be difficult to compare using standard normalization alone. This webinar explores how harmonization aligns datasets into a shared biological framework, enabling more accurate cross-study and longitudinal analysis.

Featuring insights from the Global Neurodegeneration Proteomics Consortium (GNPC), this session highlights how integrating 40,000 patient samples across 20 international research groups reveals biological signals that would otherwise remain hidden.

In this webinar you’ll learn:

  • When standard normalization falls short for cross-study comparisons 
  • How harmonization aligns data across cohorts, batches, and time 
  • How integrated datasets reveal biological signals missed in isolated analyses 

David Astling, PhD

David Astling is a service and support manager at Illumina. His team provides global scientific support, bioinformatics, and data consulting for SomaLogic customers— specializing in study design, data analysis, and extracting value from data. David has a PhD in Molecular and Cell Biology from the University of California at Berkeley. Prior to joining SomaLogic, David was a research associate in the bioinformatics core lab at the University of Colorado School of Medicine, collaborating on multiple next-generation sequencing projects.

Tala Khosroheidari

Tala Khosroheidari, Ph.D.

Tala Khosroheidari is a global leader in scientific and technical engagement across proteomics and multiomics. She joined SomaLogic in 2022 as Senior Director of Global Scientific Engagement, where she built and scaled international teams across bioinformatics, technical support, and field applications. Following the integration with Illumina, she now serves as Director of Global Service and Support, continuing to lead worldwide expertise that helps researchers translate complex data into meaningful insight about human biology.

Tala brings extensive experience from the biotechnology, proteomics, and genomics sectors. Her notable past roles include Director of Global Marketing Communication at Olink Proteomics and Development Scientist at Illumina. Known for her expertise in scientific engagement, operational leadership, and customer support, Tala has consistently demonstrated a strong track record in these areas. A pivotal moment in her career was her tenure as a Core Lab Director at the University of California, San Diego, where she gained invaluable insights into bridging academic research with assay development and translating these advancements into pharmaceutical-based clinical research.

Her academic background is equally impressive, with a Ph.D. Research Fellowship from the International Centre for Genetic Engineering & Biotechnology in Italy, an MS in Biotechnology/Bioinformatics from Johns Hopkins University, and a B.Sc. in Cellular & Molecular Biology from Azad University in Tehran, Iran. Tala’s expertise encompasses genetics, biotechnology, genomics, bioinformatics, and proteomics, establishing her as a leading authority in her field.

More than the sum of its parts: How harmonized proteomic data reveals meaning across disparate clinical cohorts

A presentation by David Astling, PhD and Tala Khosroheidari, Ph.D

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