Detection of low-abundance serum proteins associated with cardiovascular diseases for prognostic purposes

As the leading cause of death in the United States and worldwide, cardiovascular disease (CVD) includes a family of diseases that affect the heart and blood vessels. The primary origin of CVD is most often atherosclerotic in nature, in which fatty plaque deposits line arteries and obstruct circulation of blood. The etiology of CVD is multifactorial and is shaped by the interaction of genes and environment and further influenced by age and gender.