Developing microbiome-directed therapeutics for treating childhood undernutrition
Developing microbiome-directed therapeutics for treating childhood undernutrition
Abstract
This 1-hour talk covers how researchers are testing the hypothesis that perturbations in the normal development of the gut microbiome are causally related to childhood undernutrition, a devastating global health problem whose long-term sequelae include metabolic and immune dysfunction, stunting, and neurodevelopmental abnormalities, which remains largely refractory to current therapeutic interventions.
Learning objectives
This 1-hour talk covers how researchers are testing the hypothesis that perturbations in the normal development of the gut microbiome are causally related to childhood undernutrition, a devastating global health problem whose long-term sequelae include metabolic and immune dysfunction, stunting, and neurodevelopmental abnormalities, which remains largely refractory to current therapeutic interventions.
- Understand evidence that impaired postnatal development of the gut microbiota is causally related to childhood undernutrition
- Understand how preclinical gnotobiotic animal models can be used to develop new microbiota-directed therapeutics
- Understand how multiomic methods, including SomaScan® Assay proteomics, can be used to judge the efficacy and mechanism of action of these therapeutics in clinical studies
Jeffrey Gordon, MD
Director, Edison Family Center for Genome Sciences and Systems Biology, Washington University
Michael J. Barratt, PhD
Executive Director, Center for Gut Microbiome and Nutrition Research, Washington University
Developing microbiome-directed therapeutics for treating childhood undernutrition
A webinar presented by Jeffrey Gordon, MD, and Michael J. Barratt, PhD
Request more information
More webinars
WebinarIdentifying Biomarkers for IBD Diagnosis and Management
In this webinar, you’ll hear how proteomics technology can enhance the identification of biomarkers for the accurate diagnosis of Crohn’s disease and ulcerative colitis, as well as the identification of biomarkers that predict response to TNF inhibitors and other biologics in patients with IBD.
WebinarBoutique Webinar : Predicting Pregnancy Complications with High-Plex Proteomics
The interdisciplinary team, comprising 10-15 scientists and clinician-scientists, is dedicated to advancing diagnostics and therapeutics aimed at enhancing maternal and fetal care. Their primary focus lies in the development of interventions for conditions such as ectopic pregnancy and preeclampsia, alongside the creation of diagnostics to prevent stillbirth.
WebinarYoung blood for old brains and the quest to slow brain aging
Aging leads to the degradation of function in nearly all tissues and organs. This process is marked by significant shifts in gene expression and changes in concentrations of all types of biological molecules. Recent technological progress has allowed biologists to measure an unprecedented number of these molecules throughout an organism