Dual-Specific SOMAmer Reagent Identifies Key Biomarker for Aging Diseases

Discover how a dual-specific SOMAmer Reagent™ targeting the activated form of GDF11/8 uncovered a clinically relevant biomarker linked to cardiovascular events, dementia and aging. This case study shows how aptamer-based proteomics outperformed traditional methods, revealing stronger predictive power and biological specificity across large population cohorts.

What you’ll learn:

• How dual-specific SOMAmer Reagent technology detects activated GDF11/8 proteoforms that conventional assays miss
• Why distinguishing activated GDF11/8 from total protein levels reveals clinically relevant insights into aging and disease biology
• How activated GDF11/8 outperforms traditional biomarkers in predicting cardiovascular events, dementia, mortality and age-related decline
• Evidence of predictive consistency across six large, independent population cohorts