Identify protein biomarkers for aging research with the SomaScan® Assay

image of the white paper

Advanced age is the single greatest risk factor for disease; however, aging is a complex and multifactorial process, and its mechanisms are still poorly understood. It has been shown that aging activates common transcriptional patterns across most organs and tissues, such as inflammatory, stress response and transcriptional regulation pathways1, suggesting the changes are systemic and interrelated. Exposing a young, healthy organism to plasma from old mice, for example, slows down tissues regeneration in a manner that resembles aging2. Conversely, exposure to plasma from young blood is capable of restoring youthful phenotypes 3,4. Understanding the primary factors that affect tissue and organ function on a cellular level may lead to developing treatments that can help people stay healthy and live longer.

Click below for a downloadable version of this white paper

Download white paper

More White Papers

White paperEnsuring reproducibility in proteomics: Why coefficient of variation is a critical metric 

Learn more

White paperThe missing link between genes and disease: Discovery of protein quantitative trait loci using high-plex protein profiling

Learn more

White paperThe SomaScan® Assay enables discovery of blood-based biomarkers in neurodegenerative diseases

Learn more

Explore external publications in our interactive viewer