Diagnostics
Predict current and future health with SomaSignal® Tests
SomaSignal Tests give patients, providers, and payers more accurate, dynamic, and trusted health information by revealing clinically significant insights specific to the patient across many areas of health.
What are SomaSignal Tests?
SomaSignal Tests use patterns of proteins from a patient’s blood sample to predict their current health state and future disease risk from a single sample.
How do SomaSignal Tests work for clinical use?
SomaSignal Tests are based on proteins, which can change over time. Our test results change in response to therapeutic and lifestyle interventions.
SomaSignal Tests have been validated in diverse populations around the world, and also in patients with many underlying health factors.
SomaSignal Tests are run in our CLIA-certified, CAP-accredited reference laboratory at U.S. World Headquarters.
SomaSignal Tests for clinical use
Primary cardiovascular risk - 4 years
Likelihood of having a cardiovascular event (MI, stroke, heart failure-related hospitalization, cardiac death) within 4 years for patients with no prior history of cardiovascular disease
Residual cardiovascular risk - 4 years
Predicts the absolute risk of a cardiovascular event within 4 years, for patients 40 years and older, with stable cardiovascular disease, with or without type 2 diabetes, chronic kidney disease, or non-acute symptoms for suspected coronary artery disease
Heart failure prognosis - HFpEF
Predicts the risk of all-cause death within 12 months in patients over 18, with stable heart failure and preserved ejection fraction (HFpEF)
Heart failure prognosis - HFrEF
Predicts the risk of all-cause death within 12 months in patients over 18, with stable heart failure and reduced ejection fraction (HFrEF)
Kidney prognosis
Predicts the relative risk of developing at least one of the following conditions of Progressive Chronic Renal Insufficiency (PCRI) within 4 years
Dementia risk
Risk of dementia diagnosis within 20 years
Alcohol impact
Predicts impact of alcohol equivalent to more than 7 drinks per week
Body fat percentage
Predicts percentage of total body fat evaluated with DEXA scan
Cardiorespiratory fitness VO2 max
Predicts peak exercise capacity compared with pulmonary gas exchange assessment during exercise
Glucose tolerance
Predicts likelihood of having impaired glucose tolerance evaluated with 2-hour oral glucose tolerance test
Lean body mass
Predicts amount of lean body mass evaluated with DEXA scan
Liver fat
Predicts likelihood of excess liver fat as compared with liver ultrasound
Resting energy rate
Predicts resting energy expenditure compared with pulmonary gas exchange at rest
Tobacco exposure
Predicts the probability of an individual’s past or current tobacco exposure, for patients 18 years and older
Visceral fat
Predicts amount of visceral fat (in lbs) evaluated with a DEXA scan