Predict current and future health with SomaSignal® Tests

SomaSignal Tests give patients, providers, and payers more accurate, dynamic, and trusted health information by revealing clinically significant insights specific to the patient across many areas of health.

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What are SomaSignal Tests?

SomaSignal Tests use patterns of proteins from a patient’s blood sample to predict their current health state and future disease risk from a single sample.

How do SomaSignal Tests work for clinical use?

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SomaSignal Tests are based on proteins, which can change over time. Our test results change in response to therapeutic and lifestyle interventions.

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SomaSignal Tests have been validated in diverse populations around the world, and also in patients with many underlying health factors.

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SomaSignal Tests are run in our CLIA-certified, CAP-accredited reference laboratory at U.S. World Headquarters.

SomaSignal Tests for clinical use

Primary Cardiovascular Icon

Primary cardiovascular risk - 4 years

Likelihood of having a cardiovascular event (MI, stroke, heart failure-related hospitalization, cardiac death) within 4 years for patients with no prior history of cardiovascular disease

Residual Cardiovascular Icon

Residual cardiovascular risk - 4 years

Predicts the absolute risk of a cardiovascular event within 4 years, for patients 40 years and older, with stable cardiovascular disease, with or without type 2 diabetes, chronic kidney disease, or non-acute symptoms for suspected coronary artery disease

Heart Failure Icon

Heart failure prognosis - HFpEF

Predicts the risk of all-cause death within 12 months in patients over 18, with stable heart failure and preserved ejection fraction (HFpEF)

Heart Failure Icon

Heart failure prognosis - HFrEF

Predicts the risk of all-cause death within 12 months in patients over 18, with stable heart failure and reduced ejection fraction (HFrEF)

Lung Prognosis Icon

Kidney prognosis

Predicts the relative risk of developing at least one of the following conditions of Progressive Chronic Renal Insufficiency (PCRI) within 4 years

Dementia Risk Icon

Dementia risk

Risk of dementia diagnosis within 20 years

Alcohol Liver Impact Icon

Alcohol impact

Predicts impact of alcohol equivalent to more than 7 drinks per week

Body Fat Percentage Icon

Body fat percentage

Predicts percentage of total body fat evaluated with DEXA scan

Lungs VO2 Max Icon

Cardiorespiratory fitness VO2 max

Predicts peak exercise capacity compared with pulmonary gas exchange assessment during exercise

Glucose - Diabetes Icon

Glucose tolerance

Predicts likelihood of having impaired glucose tolerance evaluated with 2-hour oral glucose tolerance test

Lean Body Mass Icon

Lean body mass

Predicts amount of lean body mass evaluated with DEXA scan

Liver Fat Icon

Liver fat

Predicts likelihood of excess liver fat as compared with liver ultrasound

Resting Energy Rate Icon

Resting energy rate

Predicts resting energy expenditure compared with pulmonary gas exchange at rest

Tobacco Use Icon

Tobacco exposure

Predicts the probability of an individual’s past or current tobacco exposure, for patients 18 years and older

Visceral Fat Icon

Visceral fat

Predicts amount of visceral fat (in lbs) evaluated with a DEXA scan

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SomaSignal® tests are developed and their performance characteristics determined by SomaLogic Operating Co., Inc. They have neither been cleared or approved by the US Food and Drug Administration. SomaLogic operates a Clinical Laboratory Improvement Amendments (CLIA) certified, and College of American Pathologists (CAP) accredited laboratory.