The SomaLogic Blog

Problematic Repairs: Detecting Arthritis Sooner

Our bodies are a lot like well-constructed houses built on solid foundations. It seems like they should last forever, but the fact is that even the best houses require constant maintenance and repairs, especially as they age. And, just like houses, vigilant maintenance and earlier repairs of our bodies can often stave off bigger problems.

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From Cats to Kidneys: Sentinels of Disease

A few years ago, when I was conducting thesis research, I happened upon an article authored by an EPA researcher that stated that cats could be considered “canaries” for environment-related thyroid problems arising in humans (Dye et al., 2007). Many years later, my beloved cat Noodle B. developed thyroid problems. While being medicated, the poor thing also went on to develop kidney problems.

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I Don’t Want to, but the Body Says Better Pack It On

Winter is coming. I just know it. I do not need the changing color of tree leaves to tell me this fact. I know it because my appetite is insatiable right now. I feel like one of those brown bears that stands in the river and lets salmon continuously leap into their open mouth (though I would prefer to receive lemon-curd filled donuts).

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Braving the Perfect Storm: A Rare Disease Story

Born under atypical circumstances, a perfect storm wields unimaginable havoc. So, does a rare disease. What exactly constitutes a rare disease? In the U.S., the Orphan Drug Act of 1983 stipulated that “rarity” meant the disease affected fewer than 1 in 200,000 people, which applies to about 7,000 diseases (National Institutes of Health, 2017).

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Interpreting Genomic Art

What the …?? …. Standing back, I wonder what the artist envisioned while painting this piece. Did they just enjoy seeing the colors mix and build elaborate textures? Are they trying to communicate a new revelation about the human condition?

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Our Proteomic Fingerprint

Your genome has been hacked! …literally. Recently, a direct-to-consumer genetic test company was hacked and information about millions of people was compromised (Thielking, 2018). In this day and age, it is not surprising when a company gets hacked. What is surprising is one of the ways a genetics company can be hacked.

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Proteomics and the Warrior King

The warrior king of Sparta, King Leonidas, and his small legion found themselves arrayed against an army of hundreds of thousands. Though they fought bravely until the very end, the odds and ultimately the Fates did not favor the poor king and his legion in that gory battle of Thermopylae.

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We Are All Mutants Here

As most of you know, we are all mutants. Each of us carries variations in our gene sequence that, collectively, mark us uniquely. What does it mean to have a mutation?

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Donuts Are Not the Only Things With Holes in Them

My love-hate nemesis is back. One encounter and our paths take a long time to diverge again. Despite all my efforts, my avoidance tactics have again failed and our paths have again converged. I speak, of course, of a delicious donut and its long-term clinging to my waist line.

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