Diagnostics

Predict severe health events with SomaSignal® tests

SomaSignal tests give patients, providers, and payers more accurate, dynamic, and trusted health information by revealing clinically significant insights specific to the patient across many areas of health.

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What are SomaSignal tests?

SomaSignal tests expose early biologic signs that a patient may be headed for a severe health event, revealing whether existing treatments are adequately reducing risk or if adaptations are needed.

How do SomaSignal tests work for clinical use?

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Step 1

Order a SomaSignal test from a licensed physician

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Step 2

Visit a lab and have a blood sample drawn

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Step 3

Physician receives test results within two to three weeks and schedules a follow-up consultation

SomaSignal tests for clinical use

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CardioDMTM test

Predicts the absolute risk of a cardiovascular event within 4 years, for patients over 40,
with Type 2 Diabetes, with or without cardiovascular disease or chronic kidney disease.

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Primary cardiovascular risk - 4 years

Likelihood of having a cardiovascular event (MI, stroke, heart failure-related hospitalization, cardiac death) within 4 years for patients with no prior history of cardiovascular disease

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Secondary cardiovascular risk - 4 years

Predicts the absolute risk of a cardiovascular event within 4 years, for patients 40 years and older, with stable cardiovascular disease, with or without type 2 diabetes, chronic kidney disease, or non-acute symptoms for suspected coronary artery disease

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Cardiovascular risk in patients over 65

Predicts the absolute risk of a cardiovascular event within 4 years, for patients older than 65 years, without known cardiovascular disease, with or without type 2 diabetes

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Heart failure prognosis - HFpEF

Predicts the risk of all-cause death within 12 months in patients over 18, with stable heart failure and preserved ejection fraction (HFpEF)

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Heart failure prognosis - HFrEF

Predicts the risk of all-cause death within 12 months in patients over 18, with stable heart failure and reduced ejection fraction (HFrEF)

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Kidney prognosis

Predicts the relative risk of developing at least one of the following conditions of Progressive Chronic Renal Insufficiency (PCRI) within 4 years


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Alcohol impact

Predicts impact of alcohol equivalent to more than 7 drinks per week

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Body fat percentage

Predicts percentage of total body fat evaluated with DEXA scan

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Cardiorespiratory fitness VO2 max

Predicts peak exercise capacity compared with pulmonary gas exchange assessment during exercise

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Glucose tolerance

Predicts likelihood of having impaired glucose tolerance evaluated with 2-hour oral glucose tolerance test

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Lean body mass

Predicts amount of lean body mass (in lbs) evaluated with DEXA scan

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Liver fat

Predicts likelihood of excess liver fat as compared with liver ultrasound

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Resting energy rate

Predicts resting energy expenditure compared with pulmonary gas exchange at rest

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Tobacco exposure

Predicts the probability of an individual’s past or current tobacco exposure, for patients 18 years and older

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Visceral fat

Predicts amount of visceral fat (in lbs) evaluated with a DEXA scan

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SomaSignal® tests are developed and their performance characteristics determined by SomaLogic Operating Co., Inc. They have neither been cleared or approved by the US Food and Drug Administration. SomaLogic operates a Clinical Laboratory Improvement Amendments (CLIA) certified, and College of American Pathologists (CAP) accredited laboratory.